Royal Air Force Typhoon fighter aircraft have operated alongside France's air force in a combined operation on an hidden munitions depot in Syrian territory employed by the IS group, as stated by the UK Ministry of Defence.
The location, identified by reconnaissance, was assessed as containing munitions and bombs, the announcement noted, and was located in hills just to the north of Palmyra in the heart of Syria.
"Our aircraft employed Paveway IV guided bombs to strike a series of approach shafts providing entry to the facility... early reports indicate the objective was successfully hit," officials stated.
There was no indication of any civilian impact in the attack late on Saturday and every plane involved returned to base without incident, the defence officials confirmed.
The British jets were supported by a Voyager aerial refuelling aircraft.
The Islamic State group - referred to as ISIS - enforced militant control over large swathes of Syria and Iraq before its territorial defeat in 2019.
"This strike shows the UK's leading role, and resolve to operate in unison with our partners, to eradicate any revival of Daesh and their harmful and extremist ideologies in the region," the British Defence Secretary the minister said.
British military aircraft have conducted overwatch operations over Syria to "prevent any attempted resurgence" of Islamic State following its routing at the climactic battle in Baghuz in 2019, the ministry said.
"I must thank all the members of the UK armed forces who took part in this operation for their expertise and their valour," he commented. "They were part of numerous British personnel deployed over the festive period. This mission, to eliminate dangerous terrorists who threaten our way of life, shows how our armed forces are ready to step up, all year round, keeping Britain secure within its borders and strong abroad."
In December, the United States armed forces executed what it described as a "massive strike" against Daesh sites in Syria, after an ambush killed two American soldiers and a civilian linguist in the Palmyra area.
The UN reports Islamic State still has between 5,000 and 7,000 militants in Syria and Iraq.